Article
Linkage of the long QT syndrome to the short arm of chromosome 11: use of five highly polymorphic markers towards more detailed localization of the mutant gene.
Human genetics - 1 Oct 1995
Kainulainen K, Swan H, Miettinen H, Viitasalo M, Rovamo L, Toivonen L, Kontula K
Abstract excerpt
The long QT syndrome is an autosomally dominantly inherited cardiac disorder characterized by abnormalities of myocardial repolarization, exercise- or stress-related syncopal attacks and risk of sudden death due to cardiac arrhythmias. Genetic linkage studies have defined three LQT loci on chromo...
Topics
- Adolescent
- Adult
- Aged
- Child
- Chromosomes, Human, Pair 11
- Genetic Linkage
- Genetic Markers
- Humans
- Long QT Syndrome
- Middle Aged
- Mutation
- Pedigree
- Polymorphism, Genetic