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Article

Maternal but not paternal transmission of 15q11-13-linked nondeletion Angelman syndrome leads to phenotypic expression.

Nature genetics - 1 Jul 1992

Wagstaff J, Knoll J H, Glatt K A, Shugart Y Y, Sommer A, Lalande M

Abstract excerpt

Angelman syndrome (AS) may result from either maternally inherited deletions of chromosome 15q11-13 or from paternal uniparental disomy for chromosome 15. This is in contrast to Prader-Willi syndrome (PWS), which is caused by either paternal deletion of this region or maternal disomy for chromosome 15. However, 40% of AS patients inherit an apparently intact copy of chromosome 15 from each parent. We now describe...

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Identifiers

PMID: 1338769
DOI: 10.1038/ng0792-291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Maternal but not paternal transmission of 15q11-13-linked nondeletion Angelman syndrome leads to phenotypic expression.PMID 1338769Read ↗

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Balanced translocation 46,XY,t(2;15)(q37.2;q11.2) associated with atypical Prader-Willi syndrome.Semantic proximity Read ↗

Prader–Willi syndrome: clinical genetics, cytogenetics and molecular biologySemantic proximity Read ↗

Modification of 15q11-q13 DNA methylation imprints in unique Angelman and Prader-Willi patients.Semantic proximity Read ↗

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