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Article

Uniparental paternal disomy in Angelman's syndrome.

Lancet (London, England) - 23 Mar 1991

Malcolm S, Clayton-Smith J, Nichols M, Robb S, Webb T, Armour J A, Jeffreys A J, Pembrey M E

Abstract excerpt

Angelman's syndrome and Prader-Willi syndrome are both causes of mental retardation with recognisable, but quite different, clinical phenotypes. Both are associated with deletions of chromosome 15q11-13, of maternal origin in Angelman's and paternal in Prader-Willi. Prader-Willi can arise by inheritance of two chromosomes 15 from the mother and none from the father (uniparental maternal disomy). In 2 patients...

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Identifiers

PMID: 1672177
DOI: 10.1016/0140-6736(91)90278-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Uniparental paternal disomy in Angelman's syndrome.PMID 1672177Read ↗

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Trisomy 15 with loss of the paternal 15 as a cause of Prader-Willi syndrome due to maternal disomy.Semantic proximity Read ↗

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