Amyloid polyneuropathy with transthyretin Arg50 in a Japanese case from Osaka.

doi:10.1016/0022-510x(92)90132-5

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Article

Amyloid polyneuropathy with transthyretin Arg50 in a Japanese case from Osaka.

Journal of the neurological sciences - 1 Oct 1992

Takahashi N, Ueno S, Uemichi T, Fujimura H, Yorifuji S, Tarui S

Abstract excerpt

A Japanese patient with systemic amyloidosis associated with a transthyretin (TTR) variant Arg50 is presented. This 41-year-old man became impotent and developed decreased pain sensation in his hands, and then sensory loss and muscle wasting in his lower legs, and cardiomyopathy appeared. The sym...

Topics

Adult
Amyloidosis
Arginine
Chromatography, High Pressure Liquid
Humans
Immunohistochemistry
Male
Mutation
Pedigree
Peripheral Nervous System Diseases
Prealbumin
Sciatic Nerve

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