Mutations adjacent to the dimple of the canine parvovirus capsid structure affect sialic acid binding.

doi:10.1016/0042-6822(92)90192-r

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Article

Mutations adjacent to the dimple of the canine parvovirus capsid structure affect sialic acid binding.

Virology - 1 Nov 1992

Barbis D P, Chang S F, Parrish C R

Abstract excerpt

The erythrocyte receptor on rhesus macaque erythrocytes used by canine parvovirus (CPV) for binding in hemagglutination (HA) was examined. Erythrocyte membrane proteins were electrophoresed and blotted to nitrocellulose and probed with [125I]-labeled CPV capsids, showing seven virus-binding prote...

Topics

Animals
Binding, Competitive
Capsid
Cats
Cell Line
Dogs
Erythrocytes
Feline Panleukopenia Virus
Hemagglutinins, Viral
Hydrogen-Ion Concentration
Macaca mulatta
Membrane Proteins
Mutation
Parvoviridae
Protein Conformation
Receptors, Virus
Sialic Acids

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