Interactions of membrane excitability mutations affecting potassium and sodium currents in the flight and giant fiber escape systems of Drosophila.

Abstract excerpt

We have studied the influence of the K(+)-current mutations eag and Sh and the Na(+)-current mutation napts upon two well-defined neural circuits that underlie flight and an escape response in Drosophila, recording from dorsal longitudinal and tergotrochanteral muscles. Mutations of Sh and eag affected refractory period and following frequency, but not latency, of the jump-and-flight escape response. The napts...

Topics

• Action Potentials
• Animals
• Drosophila
• Electric Stimulation
• Flight, Animal
• Membranes
• Mutation
• Nerve Fibers
• Neural Pathways
• Phenotype
• Potassium Channels