Article
Quantitative oropharyngeal Epstein-Barr virus shedding in renal and cardiac transplant recipients: relationship to immunosuppressive therapy, serologic responses, and the risk of posttransplant lymphoproliferative disorder.
The Journal of infectious diseases - 1 Nov 1992
Preiksaitis J K, Diaz-Mitoma F, Mirzayans F, Roberts S, Tyrrell D L
Abstract excerpt
Epstein-Barr virus (EBV) infection plays a major role in the pathogenesis of posttransplant lymphoproliferative disorder (PTLD). Quantitative oropharyngeal EBV shedding measured by a DNA-DNA dot blot assay and the genotype of isolates determined by a polymerase chain reaction assay were studied i...
Topics
- Adolescent
- Adult
- Antilymphocyte Serum
- Azathioprine
- Cyclosporine
- DNA, Viral
- Female
- Follow-Up Studies
- Genotype
- Graft Rejection
- Heart Transplantation
- Heart-Lung Transplantation
- Herpesvirus 4, Human
- Humans
- Immunosuppression Therapy