Article
The CCS1 gene from Saccharomyces cerevisiae which is involved in mitochondrial functions is identified as IRA2 an attenuator of RAS1 and RAS2 gene products.
Current genetics - 1 Apr 1992
Bussereau F, Dupont C H, Boy-Marcotte E, Mallet L, Jacquet M
Abstract excerpt
The ccs1-1 mutation of Saccharomyces cerevisiae, which has been previously described, is associated with an increase in cytochrome content, in respiration, and in ATP synthesis. In addition, this mutation leads to the same phenotype as cells de-regulated in the cAMP pathway. From a yeast genomic library, we have isolated a DNA fragment in a recombinant plasmid pCD1 which complements the ccs1-1 mutation....
Topics
- Base Sequence
- Cloning, Molecular
- Cyclic AMP
- Genes, Fungal
- Genetic Complementation Test
- Mitochondria
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- Saccharomyces cerevisiae