The use of nerve growth factor as a reverse transforming agent for the treatment of neurogenic tumors: in vivo results.

doi:10.1007/BF00299412

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Article

The use of nerve growth factor as a reverse transforming agent for the treatment of neurogenic tumors: in vivo results.

Acta neuropathologica - 1 Jan 1992

Yaeger M J, Koestner A, Marushige K, Marushige Y

Abstract excerpt

The rationale behind the evaluation of natural differentiating agents, such as nerve growth factor (NGF), for reverse transforming potential is based on the theory that such compounds may represent a nontoxic means of controlling tumor growth. Previous in vitro experiments have shown that NGF is...

Topics

Animals
Antineoplastic Agents
Body Weight
Cell Transformation, Neoplastic
Clone Cells
Enzyme-Linked Immunosorbent Assay
Glioma
Immunohistochemistry
Neoplasm Transplantation
Nerve Growth Factors
Nervous System Neoplasms
Phenotype
Rats
Rats, Inbred F344
Receptors, Cell Surface
Receptors, Nerve Growth Factor

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Open in PubMed

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PMID: 1322002
DOI: 10.1007/BF00299412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1322002-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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