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Article

Transposon mutagenesis used to study the role of complement resistance in the virulence of an avian Escherichia coli isolate.

Avian diseases - 1 Jan 2000

Nolan L K, Wooley R E, Cooper R K

Abstract excerpt

The role of complement resistance in the virulence of an avian Escherichia coli isolate was examined with transposon mutagenesis. A suicide plasmid containing a kanamycin-encoding mini-transposon was used to transform a virulent complement-resistant avian E. coli isolate. A less resistant mutant was identified that contained a transposon insertion in a plasmid and in the chromosome. This loss of complement...

Topics

Animals
Autoradiography
Blotting, Southern
Chickens
Complement System Proteins
DNA Transposable Elements
Escherichia coli
Escherichia coli Infections
Mutagenesis, Insertional
Nucleic Acid Hybridization
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmids

Poultry Diseases

Transformation, Bacterial

Virulence

Source

Identifiers

PMID: 1320868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1320868-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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