Phenotypic and genotypic lineage switch of a lymphoma with shared chromosome translocation and T-cell receptor gamma gene rearrangement.

doi:10.1111/j.1349-7006.1992.tb01951.x

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Article

Phenotypic and genotypic lineage switch of a lymphoma with shared chromosome translocation and T-cell receptor gamma gene rearrangement.

Japanese journal of cancer research : Gann - 1 May 1992

Yamamoto K, Osada H, Seto M, Ogura M, Suzuki H, Utsumi K R, Oyama A, Ariyoshi Y, Nakamura S, Kurita S

Abstract excerpt

A case of non-Hodgkin's lymphoma showed a phenotypic and genotypic cell lineage switch twice during nine years of his clinical history; first, T-cell type, pleomorphic small cell lymphoma developed, followed by B-cell type, diffuse centroblastic/centrocytic lymphoma, and finally T-zone lymphoma without follicles again developed, from which AST-1 cultured cell line was established. Karyotype analysis demonstrated...

Topics

Amino Acid Sequence
Blotting, Southern
Chromosomes
DNA Probes
Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
Gene Rearrangement, delta-Chain T-Cell Antigen Receptor
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin Switch Region

Karyotyping

Leukemia, Lymphocytic, Chronic, B-Cell

Lymphoma, B-Cell

Lymphoma, Non-Hodgkin

Lymphoma, T-Cell

Male

Middle Aged

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 1319986
DOI: 10.1111/j.1349-7006.1992.tb01951.x
PMCID: PMC5918851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1319986-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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