Article
Tumor Necrosis Factor-α Stimulates the Biosynthesis of Matrix Metafloproteinases and Plasminogen Activator in Cultured Human Chorionic Cells
1 May 1992
Abstract excerpt
To investigate the role of tumor necrosis factor-alpha (TNF alpha) in advanced collagenolysis and degradation of connective tissue components in preterm parturition, the effects of human recombinant TNF alpha (hrTNF alpha) on the production of matrix metalloproteinase 1 (MMP-1)/tissue collagenase, MMP-3/stromelysin, tissue inhibitor of metalloproteinases (TIMP), urokinase type-plasminogen activator (uPa) and...
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