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Article

Characterization and regulation of the genes for a novel anthranilate 1,2-dioxygenase from Burkholderia cepacia DBO1.

Journal of bacteriology - 1 Oct 2003

Chang Hung-Kuang, Mohseni Paria, Zylstra Gerben J

Abstract excerpt

Anthranilate (2-aminobenzoate) is an important intermediate in tryptophan metabolism. In order to investigate the degradation of tryptophan through anthranilate by Burkholderia cepacia, several plasposon mutations were constructed of strain DBO1 and one mutant with the plasposon insertion in the anthranilate dioxygenase (AntDO) genes was chosen for further study. The gene sequence obtained from flanking DNA of...

Topics

Bacterial Proteins
Burkholderia cepacia
Cloning, Molecular
Gene Expression Regulation, Bacterial
Mixed Function Oxygenases
Molecular Sequence Data
Mutation
Restriction Mapping
Sequence Analysis, DNA
Substrate Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tryptophan

ortho-Aminobenzoates

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Identifiers

PMID: 13129960
DOI: 10.1128/JB.185.19.5871-5881.2003
PMCID: PMC193950

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