Article
Human papillomavirus and the three group metaphase figure as markers of an increased risk for the development of cervical carcinoma.
The American journal of pathology - 1 Feb 1992
Claas E C, Quint W G, Pieters W J, Burger M P, Oosterhuis W J, Lindeman J
Abstract excerpt
In this study, the presence of atypical mitotic figures and human papilloma virus (HPV) genomes was related to the degree of cervical intraepithelial neoplasia (CIN) or microinvasive carcinoma (MIC) as found in 94 paraffin-embedded biopsies from cervical lesions. The results showed that the frequency of three group metaphase (TGM) figures, a special kind of atypical mitotic figure, as well as the presence of HPV...
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