Genes involved in androgen biosynthesis and the male phenotype.

doi:10.1159/000182546

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Article

Genes involved in androgen biosynthesis and the male phenotype.

Hormone research - 1 Jan 1992

Waterman M R, Keeney D S

Abstract excerpt

A series of enzymatic steps in the testis lead to the conversion of cholesterol to the male sex steroid hormones, testosterone and 5 alpha-dihydrotestosterone. Mutations in any one of these steps are presumed to alter or block the development of the male phenotype. Most of the genes encoding the...

Topics

Aldehyde-Lyases
Androgens
Cholesterol Side-Chain Cleavage Enzyme
Cytochrome P-450 Enzyme System
Female
Humans
Male
Mutation
Phenotype
Sex Differentiation
Steroid 17-alpha-Hydroxylase

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