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Article

Angiotensin converting enzyme gene polymorphism is associated with severity of coronary artery disease in men with high total cholesterol levels.

Journal of applied genetics - 1 May 2012

Borzyszkowska Joanna, Stanislawska-Sachadyn Anna, Wirtwein Marcin, Sobiczewski Wojciech, Ciecwierz Dariusz, Targonski Radoslaw, Gruchala Marcin, Rynkiewicz Andrzej, Limon Janusz

Abstract excerpt

This study examines whether renin-angiotensin-aldosterone system gene polymorphisms: ACE (encoding for angiotensin converting enzyme) c.2306-117_404 I/D, AGTR1 (encoding for angiotensin II type-1 receptor) c.1080*86A>C and CYP11B2 (encoding for aldosterone synthase) c.-344C>T are associated with the extension of coronary atherosclerosis in a group of 647 patients who underwent elective coronary angiography. The...

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Share to Cholesterol, HDL
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Angiography

Share to Cytochrome P-450 CYP11B2

Share to Peptidyl-Dipeptidase A

Share to Receptor, Angiotensin, Type 1

Share to Renin-Angiotensin System

Share to Statistics, Nonparametric

Source

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Identifiers

PMID: 22307319
DOI: 10.1007/s13353-012-0083-3
PMCID: PMC3334489

Genes

ACE
AGTR1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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