Article
Translation start sequences affect the efficiency of silencing of Agrobacterium tumefaciens T-DNA oncogenes.
Plant physiology - 1 Nov 2003
Lee Hyewon, Humann Jodi L, Pitrak Jennifer S, Cuperus Josh T, Parks T Dawn, Whistler Cheryl A, Mok Machteld C, Ream L Walt
Abstract excerpt
Agrobacterium tumefaciens oncogenes cause transformed plant cells to overproduce auxin and cytokinin. Two oncogenes encode enzymes that convert tryptophan to indole-3-acetic acid (auxin): iaaM (tryptophan mono-oxygenase) and iaaH (indole-3-acetamide hydrolase). A third oncogene (ipt) encodes AMP isopentenyl transferase, which produces cytokinin (isopentenyl-AMP). Inactivation of ipt and iaaM (or iaaH) abolishes...
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