Evidence of a 1985-1987 outbreak of acute and chronic hepatitis in Egypt caused by a mutant hepatitis-B virus detected by spot-DNA hybridization test.

Article

Evidence of a 1985-1987 outbreak of acute and chronic hepatitis in Egypt caused by a mutant hepatitis-B virus detected by spot-DNA hybridization test.

The Journal of the Egyptian Public Health Association - 1 Jan 1992

Abdel-Wahab K S, Abu-Shady E A

Abstract excerpt

Sera from 65 acute and 113 chronic sporadic hepatitis were screened for serological markers of hepatitis-B virus (HBV) and hepatitis delta virus (HDV) and for HBV-DNA. The enzyme linked immune sorbent assay (ELISA) and dot-DNA hybridization tests were used. Two HBV-DNA probes and their labelling systems (biotin, radiolabelling with 32P and digoxigenin) were compared for sensitivity and specificity. The 65 acute...

Topics

Biomarkers
DNA Probes
DNA, Viral
Disease Outbreaks
Egypt
Hepatitis B
Hepatitis B virus
Humans
Mutation
Nucleic Acid Hybridization
Sensitivity and Specificity

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