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Article

The dead-end elimination method, tryptophan rotamers, and fluorescence lifetimes.

Biophysical journal - 1 Sept 2003

Hellings Mario, De Maeyer Marc, Verheyden Stefan, Hao Qiang, Van Damme Els J M, Peumans Willy J, Engelborghs Yves

Abstract excerpt

The Dead-End Elimination method was used to identify 40 low energy microconformations of 16 tryptophan residues in eight proteins. Single Trp-mutants of these proteins all show a double- or triple-exponential fluorescence decay. For ten of these lifetimes the corresponding rotameric state could b...

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Identifiers

PMID: 12944302
DOI: 10.1016/s0006-3495(03)74617-7
PMCID: PMC1303361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12944302-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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