Article
Contribution of the twin arginine translocation system to the virulence of enterohemorrhagic Escherichia coli O157:H7.
Infection and immunity - 1 Sept 2003
Pradel Nathalie, Ye Changyun, Livrelli Valérie, Xu Jianguo, Joly Bernard, Wu Long-Fei
Abstract excerpt
Shiga toxin-producing Escherichia coli O157:H7 is a major food-borne infectious pathogen. In order to analyze the contribution of the twin arginine translocation (TAT) system to the virulence of E. coli O157:H7, we deleted the tatABC genes of the O157:H7 EDL933 reference strain. The mutant displayed attenuated toxicity on Vero cells and completely lost motility on soft agar plates. Further analyses revealed that...
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