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Article

Family 18 chitinase-oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase A.

The Biochemical journal - 15 Nov 2003

Aronson Nathan N, Halloran Brian A, Alexyev Mikhail F, Amable Lauren, Madura Jeffry D, Pasupulati Lakshminarasimhulu, Worth Catherine, Van Roey Patrick

Abstract excerpt

The sizes and anomers of the products formed during the hydrolysis of chitin oligosaccharides by the Family 18 chitinase A (ChiA) from Serratia marcescens were analysed by hydrophilic interaction chromatography using a novel approach in which reactions were performed at 0 degrees C to stabilize the anomer conformations of the initial products. Crystallographic studies of the enzyme, having the structure of the...

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Identifiers

PMID: 12932195
DOI: 10.1042/BJ20030273
PMCID: PMC1223757

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Source receipt: pubmed, retrieved 7 Sept 2026.

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