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Article

Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis.

Molecular biology of the cell - 1 Aug 2003

Sandal Tone, Aumo Linda, Hedin Lars, Gjertsen Bjørn T, Døskeland Stein O

Abstract excerpt

Protein phosphatase-directed toxins such as okadaic acid (OA) are general apoptosis inducers. We show that a protein (inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5), belonging to the family of immune-associated nucleotide binding proteins, protected Jurkat T-cells against OA- and ga...

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Identifiers

PMID: 12925764
DOI: 10.1091/mbc.e02-10-0700
PMCID: PMC181568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12925764-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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