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Newcastle Disease Virus V Protein Is a Determinant of Host Range Restriction

14 Aug 2003

Abstract excerpt

It has been demonstrated that the V protein of Newcastle disease virus (NDV) functions as an alpha/beta interferon (IFN-alpha/beta) antagonist (M. S. Park, M. L. Shaw, J. Muñoz-Jordan, J. F. Cros, T. Nakaya, N. Bouvier, P. Palese, A. García-Sastre, and C. F. Basler, J. Virol. 77:1501-1511, 2003). We now show that the NDV V protein plays an important role in host range restriction. In order to study V functions in...

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Identifiers

PMID: 12915566
DOI: 10.1128/jvi.77.17.9522-9532.2003

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