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Article

The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain.

Human molecular genetics - 15 Sept 2003

Ganesh Subramaniam, Tsurutani Naomi, Suzuki Toshimitsu, Ueda Kazunori, Agarwala Kishan Lal, Osada Hiroyuki, Delgado-Escueta Antonio V, Yamakawa Kazuhiro

Abstract excerpt

Lafora disease is an autosomal recessive type of progressive myoclonus epilepsy caused by mutations in the EPM2A gene. The EPM2A gene-encoded protein laforin is a dual-specificity phosphatase that associates with polyribosomes. Because the cellular functions of laforin are largely unknown, we use...

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Source

Identifiers

PMID: 12915448
DOI: 10.1093/hmg/ddg253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12915448-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain.PMID 12915448Read ↗

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