Article
Exposure, sensitization, and mechanisms of fungus-induced asthma.
Current allergy and asthma reports - 1 Sept 2003
Kauffman Henk F, van der Heide Sicco
Abstract excerpt
Healthy individuals are continuously exposed to fungal biomass, which includes live and dead spores and fungal debris that is entrapped in the airways. In patients with asthma and/or atopy, exposure to fungal biomass might result in age-dependent sensitization and asthmatic reactions. Interaction with Toll-like receptors (TLRs) of the innate immune defense (alveolar macrophages and epithelial cells) and...
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