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Article

Rapid and sensitive assays for determination of hepatitis B virus (HBV) genotypes and detection of HBV precore and core promoter variants.

Journal of clinical microbiology - 1 Aug 2003

Hussain Munira, Chu Chi-Jen, Sablon Erwin, Lok Anna S F

Abstract excerpt

Hepatitis B virus (HBV) genotypes may influence HBeAg seroconversion rates, mutational patterns in the precore (PC) and core promoter (CP) regions, severity of liver disease, and response to antiviral treatment. Development of rapid, simple, and standardized assays to detect viral genotypes and common mutations in the PC and CP regions can accelerate research on the clinical significance of these variants. We aim...

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Identifiers

PMID: 12904378
DOI: 10.1128/JCM.41.8.3699-3705.2003
PMCID: PMC179815

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Source receipt: pubmed, retrieved 7 Sept 2026.

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