Article
Cystatin-B is expressed by neural stem cells and by differentiated neurons and astrocytes.
Biochemical and biophysical research communications - 22 Aug 2003
Brännvall Karin, Hjelm Helena, Korhonen Laura, Lahtinen Ulla, Lehesjoki Anna-Elina, Lindholm Dan
Abstract excerpt
Mutation in the gene encoding cystatin-B (CSTB) has been shown to cause progressive myoclonus epilepsy. Mice with a gene deletion of CSTB exhibit increased apoptosis of specific neurons but the physiological role of CSTB in brain cells is not fully understood. In the present study, we have examin...
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