Article
Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells.
Biochemical and biophysical research communications - 22 Aug 2003
Sinkó Emese, Iliás Attila, Ujhelly Olga, Homolya László, Scheffer George L, Bergen Arthur A B, Sarkadi Balázs, Váradi András
Abstract excerpt
Mutations in the gene coding for a human ABC transporter protein, ABCC6 (MRP6), are responsible for the development of pseudoxanthoma elasticum. Here, we demonstrate that human ABCC6, when expressed by retroviral transduction in polarized mammalian (MDCKII) cells, is exclusively localized to the...
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