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Article

ABCC6 as a target in pseudoxanthoma elasticum.

Current drug targets - 1 May 2011

Váradi András, Szabó Zalán, Pomozi Viola, de Boussac Hugues, Fülöp Krisztina, Arányi Tamás

Abstract excerpt

The ABCC6 gene encodes an organic anion transporter protein, ABCC6/MRP6. Mutations in the gene cause a rare, recessive genetic disease, pseudoxanthoma elasticum, while the loss of one ABCC6 allele is a genetic risk factor in coronary artery disease. We review here the information available on gene structure, evolution as well as the present knowledge on its transcriptional regulation. We give a detailed...

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Identifiers

PMID: 21039331
DOI: 10.2174/138945011795378612
PMCID: PMC3324121

Genes

ABCC6

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ABCC6 as a target in pseudoxanthoma elasticum.PMID 21039331Read ↗

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