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A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

4 Aug 2003

Abstract excerpt

To classify cancer specimens by their gene expression profiles, we created a statistical method based on Bayes' rule that estimates the probability of membership in one of two cancer subgroups. We used this method to classify diffuse large B cell lymphoma (DLBCL) biopsy samples into two gene expression subgroups based on data obtained from spotted cDNA microarrays. The germinal center B cell-like (GCB) DLBCL...

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PMID: 12900505
DOI: 10.1073/pnas.1732008100

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