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Article

The Drosophila misfire gene has an essential role in sperm activation during fertilization.

Genes & genetic systems - 1 Jun 2003

Ohsako Takashi, Hirai Kazuyuki, Yamamoto Masa-Toshi

Abstract excerpt

The male sterile mutation, misfire (mfr), of Drosophila melanogaster is a novel paternal effect, fertilization defective mutant that effects sperm head decondensation. mfr sperm were motile, appeared normal morphologically and were transferred to the female during copulation. However, less than 0.1% of eggs laid by females mated to mfr males hatched. Although mfr sperm entered eggs at a high frequency (93%), 99%...

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Identifiers

PMID: 12893967
DOI: 10.1266/ggs.78.253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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