Article
Sperm lacking Bindin are infertile but are otherwise indistinguishable from wildtype sperm.
Scientific reports - 3 Nov 2021
Wessel Gary M, Wada Yuuko, Yajima Mamiko, Kiyomoto Masato
Abstract excerpt
Cell-cell fusion is limited to only a few cell types in the body of most organisms and sperm and eggs are paradigmatic in this process. The specialized cellular mechanism of fertilization includes the timely exposure of gamete-specific interaction proteins by the sperm as it approaches the egg. Bindin in sea urchin sperm is one such gamete interaction protein and it enables species-specific interaction with a...
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