Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profiling in chronic myeloid leukemia patients treated with hydroxyurea.

Leukemia & lymphoma - 1 Jun 2002

Bruchova Hana, Borovanova Tereza, Klamova Hana, Brdicka Radim

Abstract excerpt

Using array technology that allows the simultaneous detection of gene expression of hundreds of genes, four patients with chronic myeloid leukemia (CML) were investigated at diagnosis and after starting administration of hydroxyurea. To detect the gene expression of peripheral blood mononuclears and granulocytes Human Cancer cDNA Array (CLONTECH) with 588 gene probes was used. Gene expression mononuclear and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimetabolites, Antineoplastic
Share to Chronic Disease
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydroxyurea

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Neoplasm Proteins

Share to Oligonucleotide Array Sequence Analysis

Share to Reproducibility of Results

Source

Identifiers

PMID: 12152998
DOI: 10.1080/10428190290026358

Genes

CDK4
CDK6
HDGF
PCNA
STAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profiling in chronic myeloid leukemia patients treated with hydroxyurea.PMID 12152998Read ↗

Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarraySemantic proximity Read ↗

Microarray-based gene expression profiling of hematologic malignancies: basic concepts and clinical applicationsSemantic proximity Read ↗

Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: Identification of deregulated genes of significance for inflammation and immune surveillanceSemantic proximity Read ↗

The impact of gene profiling in chronic myeloid leukaemia.Semantic proximity Read ↗

Differentially expressed genes responsible for insensitivity of CD34+ cells to kinase inhibitors in patients with chronic myeloid leukemiaSemantic proximity Read ↗

Clinical implications of gene expression profiling of acute myeloid leukemia.Semantic proximity Read ↗

Gene expression profiling in acute myeloid leukemia.Semantic proximity Read ↗

A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospectsSemantic proximity Read ↗

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysisSemantic proximity Read ↗

Microarray and Serial Analysis of Gene Expression Analyses Identify Known and Novel Transcripts Overexpressed in Hematopoietic Stem CellsSemantic proximity Read ↗

Comparative gene expression profile of chronic myeloid leukemia cells innately resistant to imatinib mesylateSemantic proximity Read ↗

Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.