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Article

A new role for the cell adhesion molecule L1 in neural precursor cell proliferation, differentiation, and transmitter-specific subtype generation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Jul 2003

Dihné Marcel, Bernreuther Christian, Sibbe Mirjam, Paulus Werner, Schachner Melitta

Abstract excerpt

Adhesion molecules play important roles in the development and regeneration of the CNS and PNS. We found that the immunoglobulin superfamily recognition molecule L1 influences proliferation and differentiation of neural precursor cells. Substrate-coated L1 reduced proliferation of precursor cells in a dose-dependent manner and increased neuronal and decreased astrocytic differentiation when compared with...

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Identifiers

PMID: 12878705
PMCID: PMC6740621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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