Article
[Clinical and molecular basis of androgen resistance].
Recenti progressi in medicina - 1 Nov 1992
Marcelli M, McPhaul M J
Abstract excerpt
Androgen resistance is responsible for the development of a spectrum of abnormalities of male sexual differentiation, and can be broadly divided in two categories: deficiency of 5-alpha-reductase and defects in the androgen receptor. Recent developments in the field on molecular biology have allowed the cloning and characterization of the genes responsible for both syndromes and have made it possible to detect...
Topics
- Androgen-Binding Protein
- Androgen-Insensitivity Syndrome
- Androgens
- Binding Sites
- DNA-Binding Proteins
- Estrogen Replacement Therapy
- Exons
- Fibroblasts
- Humans
- Male
- Mutation
- Oxidoreductases