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Article

Cooperative omega loops in cytochrome c: role in folding and function.

Journal of molecular biology - 1 Aug 2003

Krishna Mallela M G, Lin Yan, Rumbley Jon N, Englander S Walter

Abstract excerpt

Hydrogen exchange experiments under slow exchange conditions show that an omega loop in cytochrome c (residues 40-57) acts as a cooperative unfolding/refolding unit under native conditions. This unit behavior accounts for an initial step on the unfolding pathway, a final step in refolding, and a...

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Identifiers

PMID: 12875833
DOI: 10.1016/s0022-2836(03)00697-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12875833-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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