Article
REGULATION OF THE RATE OF ASEXUAL GROWTH AND COMMITMENT TO SEXUAL DEVELOPMENT BY DIFFUSIBLE FACTORS FROM IN VITRO CULTURES OF PLASMODIUM FALCIPARUM
1 Apr 2003
Abstract excerpt
The mechanism of switching to sexual differentiation (gametocytogenesis) of Plasmodium falciparum appears to be controlled by stochastic mechanisms that are sensitive to environmental conditions. In any given conditions, only a proportion of genetically identical parasites will become committed to sexual development. We used an experimental co-culture system to detect the presence of diffusible molecules from...
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