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Article

Identification and characterization of novel mutations implicated in congenital fibrinogen disorders

2 Jul 2018

Abstract excerpt

Unlabelled Box •Fibrinogen Disorders are characterized by variable expressivity. •Patients with fibrinogen disorders can present with bleeding, thrombosis, or both. •As previously reported, genotype‐phenotype correlations are difficult to establish. •Molecular modeling may help to further understand the effects of mutations on the mature fibrinogen protein. National Institutes of HealthR01HL120728 Maternal and...

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PMID: 30349899
DOI: 10.1002/rth2.12127

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