Estimating effective population size from samples of sequences: a bootstrap Monte Carlo integration method.

doi:10.1017/s0016672300030962

Back to search

Article

Estimating effective population size from samples of sequences: a bootstrap Monte Carlo integration method.

Genetical research - 1 Dec 1992

Felsenstein J

Abstract excerpt

We would like to use maximum likelihood to estimate parameters such as the effective population size N(e) or, if we do not know mutation rates, the product 4N(e) mu of mutation rate per site and effective population size. To compute the likelihood for a sample of unrecombined nucleotide sequences...

Topics

Base Sequence
Biological Evolution
Computer Simulation
Likelihood Functions
Models, Genetic
Monte Carlo Method
Mutation
Population Density
Software

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.