Article
[Effect of random sample size on the accuracy of nucleotide diversity estimation].
Genetika - 1 Jul 2012
Gorbachev V V
Abstract excerpt
Mathematical simulation has been used to analyze how the sample size affects the accuracy of the estimation of molecular variation in a population. The sample size was varied from 1/200 to 1/4 of the total size of the simulated population. The possible effect of the length of the nucleotide sequences compared has also been estimated; it was varied from 500 to 15 000 bp. A tendency towards underestimation of the...
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