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Article

The T(1858) variant predisposing to the precore stop mutation correlates with one of two major genotype F hepatitis B virus clades.

The Journal of general virology - 1 Aug 2003

Norder Heléne, Arauz-Ruiz Patricia, Blitz Linda, Pujol Flor H, Echevarria José M, Magnius Lars O

Abstract excerpt

The precore mutation G(1896)-->A occurs frequently in anti-HBe-positive carriers of HBsAg with T(1858) in the stem of the encapsidation signal. Hepatitis B virus (HBV) genotype F, considered an Amerindian genotype, subdivides into two clades and the precore mutation occurs in Central American F strains. To investigate the relationship between substitutions at position 1858 and these clades, the precore and small...

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PMID: 12867638
DOI: 10.1099/vir.0.19034-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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