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Article

Diversity of aspartate carbamoyltransferase genes of Trypanosoma cruzi.

International journal for parasitology - 30 Jul 2003

Nara Takeshi, Hirayama-Noguchi Yoshie, Gao Guanghan, Murai Emi, Annoura Takeshi, Aoki Takashi

Abstract excerpt

The pyrimidine-biosynthetic (pyr) gene cluster, a tandem array of pyr1-pyr3-pyr6/5-pyr2(ACT)-pyr4 from the 5' terminus, encodes all the six enzymes of de novo pyrimidine biosynthesis and occurs as a polycistronic transcription unit in Trypanosoma cruzi. The gene encoding aspartate carbamoyltransferase (ACT), the second enzyme of the pathway, was characterised using a laboratory-reared Tulahuen strain and...

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Identifiers

PMID: 12865084
DOI: 10.1016/s0020-7519(03)00095-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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