Article
A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2003
Innan Hideki
Abstract excerpt
A two-locus gene conversion model with selection is developed. Under the joint action of selection, mutation, gene conversion, recombination, and random genetic drift, approximate formulas for the expectations of the moments of allele frequencies and the expected amounts of variation within and between two loci are obtained by a diffusion method assuming relatively strong selection. It is shown that the pattern...
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