Article
Regulation of the yeast amphiphysin homologue Rvs167p by phosphorylation.
Molecular biology of the cell - 1 Jul 2003
Friesen Helena, Murphy Kelly, Breitkreutz Ashton, Tyers Mike, Andrews Brenda
Abstract excerpt
The yeast amphiphysin homologue Rvs167p plays a role in regulation of the actin cytoskeleton, endocytosis, and sporulation. Rvs167p is a phosphoprotein in vegetatively growing cells and shows increased phosphorylation upon treatment with mating pheromone. Previous work has shown that Rvs167p can be phosphorylated in vitro by the cyclin-dependent kinase Pho85p complexed with its cyclin Pcl2p. Using chymotryptic...
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