Article
Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli.
European journal of biochemistry - 1 Jul 2003
Ismail Wael, El-Said Mohamed Magdy, Wanner Barry L, Datsenko Kirill A, Eisenreich Wolfgang, Rohdich Felix, Bacher Adelbert, Fuchs Georg
Abstract excerpt
Aerobic metabolism of phenylalanine in most bacteria proceeds via oxidation to phenylacetate. Surprisingly, the further metabolism of phenylacetate has not been elucidated, even in well studied bacteria such as Escherichia coli. The only committed step is the conversion of phenylacetate into phenylacetyl-CoA. The paa operon of E. coli encodes 14 polypeptides involved in the catabolism of phenylacetate. We have...
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