Article
Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution.
Journal of molecular biology - 11 Jul 2003
Vincent Florence, Charnock Simon J, Verschueren Koen H G, Turkenburg Johan P, Scott David J, Offen Wendy A, Roberts Shirley, Pell Gavin, Gilbert Harry J, Davies Gideon J, Brannigan James A
Abstract excerpt
Esterases and deacetylases active on carbohydrate ligands have been classified into 14 families based upon amino acid sequence similarities. Enzymes from carbohydrate esterase family seven (CE-7) are unusual in that they display activity towards both acetylated xylooligosaccharides and the antibiotic, cephalosporin C. The 1.9A structure of the multifunctional CE-7 esterase (hereinafter CAH) from Bacillus subtilis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
