Article
A transposable element-mediated gene divergence that directly produces a novel type bovine Bcnt protein including the endonuclease domain of RTE-1.
Molecular biology and evolution - 1 Sept 2003
Iwashita Shintaro, Osada Naoki, Itoh Tomohito, Sezaki Mariko, Oshima Kenshiro, Hashimoto Etsuko, Kitagawa-Arita Yuko, Takahashi Ichiro, Masui Tohru, Hashimoto Katsuyuki, Makalowski Wojciech
Abstract excerpt
Ruminant Bcnt protein with a molecular mass of 97 kDa (designated p97Bcnt) includes a region derived from the endonuclease domain of a retrotransposable element RTE-1. Human and mouse Bcnt proteins lack the corresponding region but have a highly conserved 82-amino acid region at the C-terminus that is not present in p97Bcnt. By screening a bovine BAC library, we found two more bcnt-related genes: human-type bcnt...
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