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Article

Genomic analysis reveals extensive gene duplication within the bovine TRB locus

1 Jan 2009

Abstract excerpt

BACKGROUND: Diverse TR and IG repertoires are generated by V(D)J somatic recombination. Genomic studies have been pivotal in cataloguing the V, D, J and C genes present in the various TR/IG loci and describing how duplication events have expanded the number of these genes. Such studies have also provided insights into the evolution of these loci and the complex mechanisms that regulate TR/IG expression. In this...

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PMID: 19393068
DOI: 10.1186/1471-2164-10-192

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