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Article

Flavohemoglobin Hmp, but not its individual domains, confers protection from respiratory inhibition by nitric oxide in Escherichia coli.

The Journal of biological chemistry - 12 Sept 2003

Hernández-Urzúa Elizabeth, Mills Catherine E, White Gregory P, Contreras-Zentella Martha L, Escamilla Edgardo, Vasudevan Subhash G, Membrillo-Hernández Jorge, Poole Robert K

Abstract excerpt

Escherichia coli possesses a two-domain flavohemoglobin, Hmp, implicated in nitric oxide (NO) detoxification. To determine the contribution of each domain of Hmp toward NO detoxification, we genetically engineered the Hmp protein and separately expressed the heme (HD) and the flavin (FD) domains in a defined hmp mutant. Expression of each domain was confirmed by Western blot analysis. CO-difference spectra showed...

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PMID: 12826671
DOI: 10.1074/jbc.M303629200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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