Article
Human leukocyte antigen class I and II alleles and response to interferon-alpha treatment, in Taiwanese patients with chronic hepatitis C virus infection.
The Journal of infectious diseases - 1 Jul 2003
Yu Ming-Lung, Dai Chia-Yen, Chen Shinn-Cherng, Chiu Chao-Chin, Lee Li-Po, Lin Zu-Yau, Hsieh Ming-Yuh, Wang Liang-Yen, Chuang Wan-Long, Chang Wen-Yu
Abstract excerpt
To investigate the influence of immunogenetics on response to interferon (IFN)-alpha treatment, human leukocyte antigen alleles were characterized in 100 unrelated Taiwanese patients with chronic hepatitis C virus (HCV) infection. A11, B51, Cw15, and DRB1*15 were positively correlated with sustained response, whereas A24 was inversely associated with response to IFN-alpha, after adjustment for cirrhosis,...
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